Genesis Mission – A National Mission to Accelerate Science Through AI (www.energy.gov)

The Department of Energy has launched the Genesis Mission, a national initiative led by DOE and the White House OSTP that aims to build an integrated scientific platform connecting the nation’s 17 National Laboratories, supercomputers, experimental facilities, AI systems, quantum technologies, and secure multi-domain datasets. Its stated goal is to double the productivity and impact of U.S. research and innovation within a decade by enabling real‑time collaboration between humans, AI, and instruments across domains from fusion and advanced nuclear design to materials discovery, quantum computing and astrophysics. For the AI/ML community this is significant: Genesis will create high-fidelity, government-held scientific datasets and an infrastructure for training and validating models that go beyond internet-scale corpora. Key technical elements include federated integration of HPC and experimental pipelines, AI-driven digital twins and autonomous labs, AI reasoning partners for generating and verifying quantum algorithms, and closed-loop optimization for design, fabrication and grid forecasting. The platform emphasizes AI-as-discovery (not mere automation), enabling faster hypothesis testing, accelerated materials and energy innovation, and secure, mission-focused ML development. For researchers and industry, Genesis promises new benchmarks, access pathways for qualified users, and a large-scale proving ground for next‑generation AI, quantum and robotics systems with direct national-security and energy impacts.