Launching the Genesis Mission (www.whitehouse.gov)

The White House has launched the "Genesis Mission," a DOE‑led, Manhattan Project–style national initiative to build an integrated AI platform—called the American Science and Security Platform—to accelerate scientific discovery using the federal government’s vast, decades‑worth of scientific datasets. The order charges DOE (with coordination by the President’s science adviser and the NSTC) to provision supercomputing and secure cloud resources, train domain‑specific scientific foundation models, deploy AI agents to explore hypotheses and automate workflows, and enable autonomous and AI‑augmented experimentation and manufacturing. The mission explicitly targets national priorities such as advanced manufacturing, biotechnology, critical materials, nuclear fission/fusion, quantum information, and semiconductors. Key technical requirements and timelines are specified: within 90 days DOE must inventory compute/storage/network resources (including national lab HPC and industry partners); within 120 days it must identify initial data and model assets and risk‑based cybersecurity plans; within 240 days it must review robotic lab and production capabilities; and within 270 days it should demonstrate an initial operating capability for at least one challenge. The order also mandates secure data access (federal, proprietary, open, and synthetic), model‑sharing and IP frameworks, interagency coordination, public‑private partnerships, prize funding, and workforce fellowships. For AI/ML practitioners, Genesis promises massive compute+data scale and integrated tooling for scientific foundation models and automated experimentation—while raising governance, cybersecurity, IP and supply‑chain considerations that will shape research, commercialization, and national‑security tradeoffs.